Most of my comedy writing happens through improvisation on stage; doing it in the moment.

It seems people are more willing to let other people control their minds now and recreational drug use doesn't seem to have that same renegade sense of adventure that it once did.

I'm not for everyone. I'm barely for me.

Maybe depression is the most reasonable response to all the crap around us. Maybe it's the happy people who need medication.

That’s the big challenge of life—to chisel disappointment into wisdom so people respect you and you don’t annoy your friends with your whining.

Buying my wife a gun sort of like me saying, ' You know, I kinda want to kill myself, but I want it to be a surprise'.

You can't avoid pain in life. It's how you handle pain, that's what defines you.

In most cases the only difference between depression and disappointment is your level of commitment.

Well, evolution's just a theory.' And, I'm thinking to myself, 'Well, thank goodness gravity's a law.'

We need the children of Indonesia and the Philippines to manufacture our freedom of choice.

Faith in the face of disappointment is only enhanced by laughter in the face of pain.

We all know the protocol. But more powerful than our protocol is our grooming to believe in something more.

The last image I registered was Ethan and my hand – linked, bound and unbreakable.

Sometimes bliss can only be found in the serenity of darkness.

Man has been slipping backward for ages. The more advanced we became the more primitive we grew.

Service is the highest form of worship.

O wild, dark flower of woman, Deep rose of my desire, An Eastern wizard made you Of earth and stars and fire.

But honestly, if you do a rigorous survey of my work, I'll bet you'll find that biology is a theme far more often than physical science.

I am willing to be annoying if that's what was necessary.

If you only talk to a person's head and not their heart people won't listen to you.

[On turning down an invitation to appear for four minutes on the Ed Sullivan Show:] Honey, it takes Moms four minutes just to get on the stage.