There's no ironic appreciation of things we love, even of things that are in fact ridiculous, which a hipster might take and own and show the world the humor in it.

We're not in an information age anymore. We're in the information management age.

Nerds get caught up in minutiae, because there is a tremendous and fulfilling sense of control in understanding every single detail of a thing more than any other living creature.

Bowling is all physics and energy distribution. It's F = ma. So it is actually one of the most science-y sports, because it literally is just a ball and a surface and objects to knock down.

When you hang around a lot of comedians long enough, you realize there's a certain gene, in every comedian. It's why we get hyper-analytical about things.

I do seem like the kind of guy who'd be obsessive about Rubik's Cubes.

No matter what tricks you use or what decisions you make, go easy on yourself as someone who's on a never-ending quest for improvement.

Steal moments of happiness if you have to, and then collect them until they are the dominant images in your psyche.

I almost think of nerd brains as rattlesnake venom; like, you can milk it. You can milk the pulpy venom out of the nerd brain and use it for good if you want to.

Humans cannot produce viable offspring with our closest animal cousin: the chimpanzee. We cannot impregnate a chimp. So you know what that means? No condoms.

I've gone from being bullied by jocks as a kid to being bullied by nerds as an adult.

All of our technology is completely unnecessary to a happy life.

It's fashionable for modern actors to talk about getting 'inside' a character. But you can't get to the inside without getting the outside right first.

Romance is all about making a story out of our love.

Brother and Sister So & So are not your standard; Jesus is.

The picture must be... a revelation, an unexpected and unprecedented resolution of an eternally familiar need.

The biggest disease today is not leprosy or tuberculosis, but rather the feeling of being unwanted.

I paint very directly. I go from top to bottom. When I get to the floor, the painting is finished.

I'm not Irish. Just because I have red hair doesn't mean I'm a lucky charm, you know?

The lesson of history is that no one learns.

Confidence is key. Sometimes, you need to look like you're confident even when you're not.