The thing you realize pretty quickly, though, is that being in front of an audience whose job it is to laugh is a big pressure if the writing is not hilarious.

I'm doing a very funny show in which we talk about issues. I speak at Aids charities and things. It's great to do something fun with our days and yet we're told we're doing something important.

I remember I had scenes with Melinda McGraw in "Ides Of March" that I didn't have in "Video Vigilante," but I can't quite picture that other character. But it was Vancouver, and that year was crazy

As a television actor, there's a power you're given to use your image to do something valuable. As a parent, these messages are particularly important to me.

The Andromeda strain is a killer disease that they've got to prevent from spreading to being 100 percent contagious. It's another one where we're racing to save humanity.

My most romantic job: I was a manager at Baskin-Robbins.

When I read the script for Will & Grace in 1998, I knew I was the only guy for the part.

I always get a little uppity when I hear the phrase 'TV actor.' It's like saying you're a magazine reporter. I was in the theater for ten years before I ever had a TV audition.

I was raised on 'Get Smart' and 'All in the Family' and 'M.A.S.H.,' and certainly when 'Cheers' came along, that was a big one.

I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done.

As much as I loved [Al] Pacino and [Robert] De Niro and wanted to be a dramatic actor, I also grew up on sitcoms.

There is nothing you lack and all you will find

You knew the sweetness of now, now, TONIGHT! who cares for tomorrow, tomorrow is nothing, yesterday is over and done, tonight live, tonight!

I like meeting all my fans and signing autographs, although it can all get a bit crazy. Yesterday, for example, a boy just came over and planted a big kiss on my face! I was like, 'Hello?'

All of us want to be part of something bigger than ourselves, something that matters.

A plot without action is like pasta without garlic, like Dolly Parton without cleavage, and like a writer without his similes.

Rosabelle - answer - tell - pray, answer - look - tell - answer, answer - tell.

I fell in love with doing yoga.

The United States is not a Christian nation any more than it is a Jewish or a Mohammedan nation.

Eastern Connecticut is very different from Western; we're more liverwurst than pâté, more bowling than polo.

The most beautiful, perhaps the only true philosophical song existing in any known tongue ....perhaps the deepest and loftiest thing the world has to show.