When I left Maine, I always wanted to be a working actor. I never cared too much about being the star. I just wanted to do the work and get on with it.

The best part about being married is feeling centered. Nothing else matters so much as long as you can come home and be with your family.

I think dreams can come true, but not necessarily like fairy-tales. It's not always so perfect like that.

I know it can be dangerous, but I love racing. I worry my wife, but she knows it's important to me.

People sometimes mistake being serious with being taken seriously.

Now I'm just known as McDreamy, I've lost all identity as Patrick Dempsey, I'm now McDreamy.

I think fame is one of those things where you have a window of opportunity and you have a certain amount of trust from the fans and without that you don't have a career.

Fame is fleeting. Sometimes people like you, sometimes they don’t. Not all people are going to like you.

A wedding is like a funeral, but with musicians.

Eventually feels a lot different than actually.

The key to a successful marriage is accepting that you're not going to change the other person. And the words "Yes, dear. Whatever you want.

Beautiful enough to lure in prey, he said. Strong enough to clamp down and destroy, he said.

What's cool about indie rock is that one band can do effectively the same thing as another band, and one band nails it, and the other one doesn't. I like that elusiveness.

Thus human beings judge of one another, superficially, casually, throwing contempt on one another, with but little reason, and no charity.

Awareness is learning to keep yourself company. And then learn to be more compassionate company, as if you were somebody you are fond of and wish to encourage.

People in New Zealand go out of their way to not be impressed by things.

It is going to be changed to straight P. Diddy. You could call me P. or Diddy, or P. Diddy. I just want something fresh, man.

When I first got the job, I was told nothing about my character. She's an anthropologist and she's tough, she's a female Indiana Jones. That's what I went into [Lost] knowing.

So many of these comics are just frustrated singers or actors - they want to get a gig doing a sitcom. It's paint-by-the-numbers comedy, lame joke-telling. They're drawn to it as a career move.

My mind works in idleness. To do nothing is often my most profitable way.

I've been attracted to imagery and occasionally I've drawn from it, but I never thought I'd be painting these paintings. I didn't have any desire to. I didn't think there was any reason to.