To out-group-members, oxytocin makes you crappier - less cooperative and more preemptively aggressive. It's not the luv hormone. It's the in-group parochialism/xenophobia hormone.

Stress is not a state of mind... it's measurable and dangerous, and humans can't seem to find their off-switch.

We live well enough to have the luxury to get ourselves sick with purely social, psychological stress.

The purpose of science is not to cure us of our sense of mystery and wonder, but to constantly reinvent and reinvigorate it.

An open mind is a prerequisite to an open heart.

But if you get chronically, psychosocially stressed, you're going to compromise your health. So, essentially, we've evolved to be smart enough to make ourselves sick.

The less it is possible that something can be, the more it must be.

Essentially, we humans live well enough and long enough, and are smart enough, to generate all sorts of stressful events purely in our heads.

We all seek out stress. We hate the wrong kinds of stress but when it's the right kind, we love it - we pay good money to be stressed by a scary movie, a roller coaster ride, a challenging puzzle.

What does the frontal cortex do? Gratification postponement, executive function, long-term planning, and impulse control. Basically, it makes you do the harder thing.

If a rat is a good model for your emotional life, you're in big trouble.

Fairness does not mean everyone gets the same. Fairness means everyone gets what they need.

Things is very primitive in the jungle - no place to shit, sleep on the ground like an animal, eat out of cans, no place to take a bath or nothing, clothes is all rotting off.

We ought to give each other, a chance to change.

Everybody needs his memories. They keep the wolf of insignificance from the door.

Following straight lines shortens distances, and also life.

I mean, I don't mind promoting a movie, or talking to the press if it's going to be used in some way

I've never been mean-spirited, in my opinion. I never did anything below the belt.

Women are so enigmatical - some in everything - all in matters of the heart. Don't they sometimes actually admire what is repulsive?

I’m not trying to play the guitar. I’m trying to play music.

Why be a governor or senator when you can be king of Disneyland?