Just learn the whole script before you start shooting. That makes shooting a joy. Even if they rewrite, it's easy.

I'm a firm believer that character is highly overrated. Character is a trick that we do with the audience's collusion.

I was a dog in a past life. Really. I'll be walking down the street and dogs will do a sort of double take. Like, Hey, I know him.

That red carpet has to be felt to be believed.

Oh yeah, that's the Holy Grail, Pirates of the Caribbean. Johnny Depp, he's the real deal, isn't he? He doesn't get the girl, and he doesn't care.

Shameless is a rough show, and it’s not for everyone, but it’s also beautiful.

It's hard to be depressed around a ukulele. You just pick it up and you're halfway home.

I'll tell you this about the Oscars - they're real.

There are some older women out there who are just knockouts, real beauties, and they're not getting the roles they should.

Everyone hooks up with George Clooney. He's a genuinely cool guy. He's using his powers for good.

You should know the lines, be prepared, get sleep, and have the script analyzed so you're ready to rock and roll.

Science is fun. Science is curiosity. We all have natural curiosity. Science is a process of investigating. It's posing questions and coming up with a method. It's delving in.

One of the most destructive anti-concepts in the history of moral philosophy is the term 'duty.

We consider that the lives of all beings are just as precious as our own, and through this we develop a sense of concern for others.

Learning is the process whereby knowledge is created through the transformation of experience

The most important thing is to live a fabulous life. As long as it's fabulous I don't care how long it is.

Jerusalem meant one thing for Jesus: certain death.

I would tell myself the same thing that I continue to tell myself today, which is don't sweat the small things.

Time travel and teleportation will have to wait. It may take centuries to master these technology.

Don’t think. Thinking is the enemy of creativity.

True repentance includes sorrow for sin and contrition of heart. It breaks the heart with sighs and sobs and groans.