It's hard to be depressed around a ukulele. You just pick it up and you're halfway home.

I'm a firm believer that character is highly overrated. Character is a trick that we do with the audience's collusion.

I was a dog in a past life. Really. I'll be walking down the street and dogs will do a sort of double take. Like, Hey, I know him.

That red carpet has to be felt to be believed.

Oh yeah, that's the Holy Grail, Pirates of the Caribbean. Johnny Depp, he's the real deal, isn't he? He doesn't get the girl, and he doesn't care.

Shameless is a rough show, and it’s not for everyone, but it’s also beautiful.

I'll tell you this about the Oscars - they're real.

There are some older women out there who are just knockouts, real beauties, and they're not getting the roles they should.

Everyone hooks up with George Clooney. He's a genuinely cool guy. He's using his powers for good.

You should know the lines, be prepared, get sleep, and have the script analyzed so you're ready to rock and roll.

I love metaphor the way some people love junk food.

For somehow this is tyranny's disease, to trust no friends.

So be sure when you step, Step with care and great tact.

You conquered the landscape with the soles of shoes, not the tires.

Art is the daughter of pleasure.

I just like to switch things up all the time. Like when it comes to singing, I try to find a different character for each song.

It is imperative to base your life on yourself, to take responsibility for your own happiness.

Why should I want what's good for me?' Beatrice asked him, smiling. 'Is that what you want for yourself - only what's good for you?

I don't really use YouTube that much. I am a very Internet-oriented person, but I'm more of a Twitter freak - I'm always on Twitter. Or chatting with friends.

You [should] persist even though there are some short-term stresses and even though there is some uncertainty, because it's the right thing to do.

If Queen Elizabeth knighthooded me and I would get the title Sir Usain Bolt. That sounds very nice.