If you want to make a [rhubarb] pie from scratch, first you have to create the universe.

Somewhere, something incredible is waiting to be known.

It is far better to grasp the universe as it really is than to persist in delusion, however satisfying and reassuring.

The nitrogen in our DNA, the calcium in our teeth, the iron in our blood, the carbon in our apple pies were made in the interiors of collapsing stars. We are made of starstuff.

Imagination will often carry us to worlds that never were. But without it we go nowhere.

I don't want to believe. I want to know.

The absence of evidence is not the evidence of absence.

The brain is like a muscle. When it is in use we feel very good. Understanding is joyous.

We live in a society exquisitely dependent on science and technology, in which hardly anyone knows anything about science and technology.

For small creatures such as we the vastness is bearable only through love.

You have to know the past to understand the present.

You see why I married her, Mycroft? The exquisite juxtaposition of ladylike threads and backhanded compliments proved irresistible.

Always have a list of what you want to achieve in life

The backside of mountain is a fight against human nature, " he said. "You have to care as much about yourself on the way down as you did on the way up.

Altruism is the best source of happiness. There is no doubt about that.

Unmitigated seriousness is always out of place in human affairs.

To lese-majeste and contempt of court, we must add the crime of lese-million, that fearful indignity we visit on the rich when we expose the impotence of gold.

Well, better expelled and able to defend yourselves than sitting safely in school without a clue," said Sirius.

The sharper the competition, the better it serves its social function to improve economic production.

Used to ride with him to Brooklyn, Lewis and Halsey, co chocolate thai, vernon style and burn it down

People who have expertise or the luck to have rehearsal time with cameras have it over people who don't.