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There are 41 million people who do not have access to a toilet in Pakistan and as a result they are defecating in the open. And open defecation has significant health and nutritional consequences.
Of those hundreds of lawsuits [for Donald Trump], we're told 30 are significant. There's pressure for him to settle that suit before he goes into the office.
It is the main earthly business of a human being to make his home, and the immediate surroundings of his home, as symbolic and significant to his own imagination as he can.
When you're a big enough part of the process that the Writers Guild gives you a lot of credit, that's a good thing. It tells me that I've had a significant impact on the film as a writer.
The discoveries which we make abroad are special and particular; those which we make at home are general and significant. The further off, the nearer the surface. The nearer home, the deeper.
The most pressing and significant problems in the global economy are unsustainable structural issues with regard to the E.U. - fiscal deficits and the structure of the E.U. itself.
I will be as careful as I can in making the most significant decisions any president and commander-in-chief can make about sending our men and women into harm's way.
If Vancouver did not succeed as Starbucks from '87 on, our entire international business, which is now thousands of stores and a significant amount of growth and profit, may not have existed.
I hope that each of you girls will become an individual of significant worth and a person of virtue so that your contributions are maintained in both human and eternal terms.
Normally death scenes are good, if you have a significant death scene and it means something it's like the audience has an attachment to you being killed that's a good thing.
A modest critique of an age in which an actor is the President, in which fashion models are asked for their opinions, in which getting into a nightclub is seen as a significant human achievement.
We only need to walk or bike ten percent of the time to make a significant change in society. That is just two days of walking, bicycling or taking transit per month for a typical commuter.
He remained heartbroken, which meant one of two things: either his love was pure and true and earthshakingly significant; or he was addicted to feeling forlorn, he liked being heartbroken.
Do I think reality TV is going to be a path to politics in a significant way? Eh, I don't know. Trump is a very specific case. It's really gonna be hard to replicate that.
Fame is a by-product which you have to deal with in a sensible way. To believe that it is anything more significant than that is deeply self-deceptive.
The truth of the matter is there is significant debate among judicial scholars today as to whether or not we've gone off on the wrong path with regard to Supreme Court decisions.
Especially in the case of India and Pakistan, it's very clear that significant parts of the elites in both countries view having nuclear weapons as a ticket to prestige.
I know few significant questions of public policy which can safely be confided to computers. In the end, the hard decisions inescapably involve imponderables of intuition, prudence, and judgment.
So while there is no evidence at all that Iran has any significant quantity of nuclear material or any nuclear weapons, Iran is a much more difficult nuclear issue to resolve for the United States.
An occupying power has no right to make significant alterations in the character of the occupied society, to change the laws all around, without a strong security reason and so forth.
The past was nothing to her; offered no lesson which she was willing to heed. The future was a mystery which she never attempted to penetrate. The present alone was significant.
It's very different than it use to be. I think everybody has a lot more experience in how to be in a relationship - whether it's a marriage or a significant other or a business or a friend.
No company that I ever hacked into reported any damages, which they were required to do for significant losses. Sun didn't stop using Solaris and DEC didn't stop using VMS.
It won't make for a quiet life but it will make for an interesting paper vastly more significant because it is doing something only a daily paper can do.